Hoodoo is a primarily African-American synthesis of African spirituality, which is polytheist when it comes to the 7 african powers, applications of Biblical and Saint practices, and slave and share-holder folk magic. Although Hoodoo is not witchcraft, it has influenced many forms of American folk magic and witchcraft through migration and cultural exchange.
It is not surprising that due to the melting pot that is America, European grimoires made their way into African American Hoodoo, for example the Pow Wow, which is Pennsylvania Dutch and the Sixth and Seventh book of Moses made their way into Hoodoo.
As these books have huge influence on American Traditional forms of witchcraft, it is not surprising to find that Hoodoo and Appalachian and Ozark magic have enough in common to share and exchange techniques and methods.
As with most British Witchcraft, American Witchcraft is often either Christian, Heretical Christian or Dual Observance in nature. Although paganism is not really common, fairy faith and spirit working and making pacts with devils comes up more.
Is it possible to meld the two in a manner that is respectful? I believe so, but its up for argument. Some modern streams of witchcraft that I think respectfully bring together many influences are Feri (especially earlier less publicized forms), Italian American witchcraft, and Cultus Sabbati (which has British and American branches), and American German witchcraft, and of course the Ozark and Appalachian witchcraft. Some of these have included elements of Hoodoo into them, some haven’t—its hard to separate Both England and America are very multi-cultural melting pots—and its hard to separate out where everything came in and get to some supposed “pure form”. As something may have come into Hoodoo through a European or Pennsylvania Dutch grimoire and then was then influenced back onto other forms of American folk magic again.
So the short answer is yes, Hoodoo can’t help but be a part of many forms of American Traditional Witchcraft.